VanderPlate C
Health Psychol. 1984;3(3):253-72. doi: 10.1037//0278-6133.3.3.253.
Multiple sclerosis (MS) is a chronic, progressive neurological disease that produces demyelination of the CNS nerve fibers. With onset most often in young adulthood, the disease produces a variety of neurological symptoms and follows an unpredictable course characterized by exacerbations and remissions. This article reviews the literature on psychological aspects of MS including early psychoanalytic studies and more current psychosocial research. Literature on the relationship between stress and symptoms, and the extent of cognitive impairment experienced is reviewed. A view of psychosocial adjustment to MS based upon an adaptive coping model, and a psychological treatment approach suited to the special needs of individuals with MS are discussed. Finally, a biopsychosocial research model is recommended due to the complex, interactive nature of MS and unique research difficulties it presents.
多发性硬化症（MS）是一种慢性进行性神经疾病，会导致中枢神经系统神经纤维脱髓鞘。该疾病最常于成年早期发病，会产生多种神经症状，其病程不可预测，具有病情加重和缓解的特点。本文回顾了有关MS心理方面的文献，包括早期的精神分析研究和当前的社会心理研究。还回顾了关于压力与症状之间关系以及认知障碍程度的文献。讨论了基于适应性应对模型的MS社会心理调适观点，以及适合MS患者特殊需求的心理治疗方法。最后，鉴于MS的复杂性、交互性本质及其带来的独特研究困难，推荐采用生物心理社会研究模型。
