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从冠欧螈(Triturus cristatus)皮肤毒液中分离主要毒性蛋白。

Isolation of the major toxic protein from the skin venom of the crested newt, Triturus cristatus.

作者信息

Jaussi R, Kunz P A

出版信息

Experientia. 1978 Apr 15;34(4):503-4. doi: 10.1007/BF01935955.

DOI:10.1007/BF01935955
PMID:639950
Abstract

A new protein, of molecular weight 160,000, was isolated from the skin venom of the crested newt and partially characterized by bioassays and biochemical methods. This protein shows the same functional properties as the crude venom, which produces convulsions in mice and is cytotoxic.

摘要

从冠螈的皮肤毒液中分离出一种分子量为160,000的新蛋白质,并通过生物测定和生化方法对其进行了部分表征。这种蛋白质具有与粗毒液相同的功能特性,粗毒液会使小鼠惊厥且具有细胞毒性。

相似文献

1
Isolation of the major toxic protein from the skin venom of the crested newt, Triturus cristatus.从冠欧螈(Triturus cristatus)皮肤毒液中分离主要毒性蛋白。
Experientia. 1978 Apr 15;34(4):503-4. doi: 10.1007/BF01935955.
2
Morphometric study of the diploid karyotype of the crested newt, Triturus cristatus carnifex (Laur.).有冠蝾螈(Triturus cristatus carnifex (Laur.))二倍体核型的形态测量研究。
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Ann Anat. 2023 Aug;249:152097. doi: 10.1016/j.aanat.2023.152097. Epub 2023 Apr 1.
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Effects on spermatogenesis of permanent lesions to the rostral preoptic area in the crested newt (Triturus cristatus carnifex Laur.).
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A study of meiosis in interracial hybrids of the newt, Triturus cristatus.关于蝾螈(Triturus cristatus)种间杂种减数分裂的研究。
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A transplantable fibroma of the skin in the newt Triturus taeniatus.虎纹钝口螈皮肤的一种可移植性纤维瘤。
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The contribution of the chromosomes to the telophase nucleus in cultures of fibroblasts of the adult crested newt Triturus cristatus carnifex.成年有冠蝾螈(Triturus cristatus carnifex)成纤维细胞培养中染色体对末期细胞核的贡献。
Exp Cell Res. 1959 Oct;18:197-216. doi: 10.1016/0014-4827(59)90001-1.
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The toxicity of manganese ethylenebisdithiocarbamate to the adult newt, Triturus cristatus.亚乙基双二硫代氨基甲酸锰对成年冠欧螈的毒性。
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[Heteroplastic regeneration of chimeric extremities in Triturus vulgaris and Triturus cristatus].[普通蝾螈和冠北螈嵌合肢体的异种再生]
Experientia. 1955 Apr 15;11(4):154-5. doi: 10.1007/BF02158479.

本文引用的文献

1
The gel-filtration behaviour of proteins related to their molecular weights over a wide range.蛋白质的凝胶过滤行为与其在很宽范围内的分子量相关。
Biochem J. 1965 Sep;96(3):595-606. doi: 10.1042/bj0960595.
2
The estimation of polypeptide chain molecular weights by gel filtration in 6 M guanidine hydrochloride.在6M盐酸胍中通过凝胶过滤法估算多肽链分子量
J Biol Chem. 1969 Sep 25;244(18):4989-94.
3
The reliability of molecular weight determinations by dodecyl sulfate-polyacrylamide gel electrophoresis.通过十二烷基硫酸钠-聚丙烯酰胺凝胶电泳测定分子量的可靠性。
J Biol Chem. 1969 Aug 25;244(16):4406-12.
4
A modified two-dimensional gel system for the separation and radioautography of microgram amounts of ribosomal proteins.一种用于微克量核糖体蛋白质分离和放射自显影的改良二维凝胶系统。
Methods Enzymol. 1974;30:526-39. doi: 10.1016/0076-6879(74)30052-3.