McKishnie J D, Muir J M, Girvan D P
Department of Anaesthesia, Victoria Hospital, London, Ontario.
Can Anaesth Soc J. 1983 May;30(3 Pt 1):295-8. doi: 10.1007/BF03013811.
Anaesthesia-induced rhabdomyolysis (AIR) is a rare but serious complication of general anaesthesia. We report the occurrence of this event in a previously healthy three-year-old male, with a strongly positive family history of Duchenne muscular dystrophy. Following an uneventful anaesthetic, which included succinylcholine, myoglobinuria developed and led to renal failure which fortunately reversed with conservative treatment. Based on review of reports of similar cases, it is clear that succinylcholine should be avoided in paediatric patients with known myopathy or at high risk for latent myopathy.
麻醉诱导性横纹肌溶解症（AIR）是全身麻醉一种罕见但严重的并发症。我们报告了一名既往健康的三岁男性发生此事件，其患有杜氏肌营养不良症的家族史呈强阳性。在一次包括琥珀酰胆碱的麻醉过程顺利后，出现了肌红蛋白尿并导致肾衰竭，幸运的是经保守治疗后病情逆转。基于对类似病例报告的回顾，很明显，对于已知患有肌病或有潜在肌病高风险的儿科患者，应避免使用琥珀酰胆碱。
