Henderson W A
Can Anaesth Soc J. 1984 Jul;31(4):444-6. doi: 10.1007/BF03015422.
A case history is presented of a three-year-old boy with unsuspected Duchenne muscular dystrophy, who suffered a cardiac arrest following the administration of a single dose of succinylcholine during a halothane anaesthetic. The arrest was associated with lack of fasciculations, muscle rigidity, hyperkalemia, myoglobinuria, and massive elevation of serum creatine phosphokinase. Asystole was prolonged and refractory to treatment, although cardiac activity was eventually restored. The possible cause of the circulatory collapse is discussed and reports of similar cases reviewed. Neither succinylcholine nor halothane should be employed in cases with known or suspected Duchenne muscular dystrophy.
本文报告了一例三岁男孩的病例，该男孩患有未被怀疑的杜氏肌营养不良症，在氟烷麻醉期间单次注射琥珀酰胆碱后发生心脏骤停。心脏骤停与无肌束震颤、肌肉强直、高钾血症、肌红蛋白尿以及血清肌酸磷酸激酶大幅升高有关。心搏停止持续时间长且对治疗无效，尽管心脏活动最终恢复。文中讨论了循环衰竭的可能原因，并回顾了类似病例的报告。已知或疑似杜氏肌营养不良症的病例均不应使用琥珀酰胆碱或氟烷。
