Anderson M, Brassington D, Bolger J
Br Med J (Clin Res Ed). 1983 Jan 1;286(6358):32-6. doi: 10.1136/bmj.286.6358.32.
An intravenous cytotoxic reconstitution service has proved extremely popular with both medical and nursing staff. Since the pharmacy has taken over the responsibility for presenting these medicines in a readily usable form, many potential hazards to inexperienced medical staff have been eliminated, and much time and money have been saved. The pharmacists are in an excellent position to offer advice on many aspects of excellent position to offer advice on many aspects of cytotoxic treatment and are well equipped to spot prescription errors. They are often asked to supply information concerning rates and methods of administration as well as compatibility data of different diluents with various cytotoxic agents. The eventual objective of the service is to provide reconstituted cytotoxic drugs for all patients in the pharmaceutical district receiving chemotherapy. As it is not practical to have pharmacists available 24 hours a day, some form of batch production of syringe-loaded drugs could be used. In the immediate future the practicality of storing syringe-loaded drugs in a deep freeze (at -20 degrees C) with rapid thawing will be considered.
静脉注射细胞毒性药物复溶服务在医护人员中极受欢迎。自从药房承担起以易于使用的形式提供这些药物的责任后，消除了许多 inexperienced 医务人员面临的潜在风险，节省了大量时间和金钱。药剂师处于极佳位置，能就细胞毒性治疗的诸多方面提供建议，且具备发现处方错误的能力。他们经常被要求提供有关给药速率和方法以及不同稀释剂与各种细胞毒性药物的配伍数据的信息。该服务的最终目标是为该药学区域内所有接受化疗的患者提供复溶后的细胞毒性药物。由于让药剂师一天 24 小时随时待命不切实际，可采用某种形式的预装注射器药物批量生产。在不久的将来，将考虑把预装注射器药物储存在深度冷冻（-20 摄氏度）并快速解冻的可行性。 （注：原文中inexperienced拼写有误，应为experienced ）
