Weber T R, West K W, Grosfeld J L
Am J Surg. 1983 Feb;145(2):202-4. doi: 10.1016/0002-9610(83)90062-4.
Broviac central venous catheters were utilized in 101 infants and children for total parenteral nutrition, administration of chemotherapy and antibiotics, and venous blood sampling over a 30 month period. A low sepsis rate (6 percent) despite the immunosuppressed condition of many of the patients and the demonstrated versatility of each catheter attests to its wide and safe applicability in this age group. Three infected catheters were sterilized by infusion of specific antibiotics through the catheter, a technique which may prove particularly valuable in patients with limited venous access.
在30个月的时间里，101名婴幼儿和儿童使用了Broviac中心静脉导管进行全胃肠外营养、化疗药物及抗生素给药以及静脉血采样。尽管许多患者处于免疫抑制状态，但败血症发生率较低（6%），而且每个导管都显示出多功能性，这证明了其在该年龄组中广泛且安全的适用性。3根感染的导管通过经导管输注特定抗生素得以消毒，这项技术在静脉通路有限的患者中可能证明特别有价值。
