Hartley R M, Velez R, Morris R W, D'Souza M F, Heller R F
Br Med J (Clin Res Ed). 1983 Jan 22;286(6361):287-9. doi: 10.1136/bmj.286.6361.287.
Patients with newly found raised blood pressure are known to have lower pressures at subsequent measurements even when not treated. A study was undertaken to determine the extent to which (a) the number of follow-up measurements and (b) the duration of the intervals between them contributed to this fall in pressure. In 42 general practices 110 patients were identified as having for the first time a diastolic pressure (phase V) greater than 90 and less than 110 mm Hg. Both diastolic and systolic pressures were appreciably lower when measured at return visits when compared with the first measurement. The systolic pressure dropped appreciably in the intervals between the first and the second visits and again between the second and third visits. The diastolic pressure fell appreciably only between the first and second visits. The duration of the interval between visits was not associated with a fall in either systolic or diastolic pressure, but the number of measurements was. This pattern of fall in pressure was not affected by the patient's age or sex. From these results we conclude that patients with newly identified blood pressures that are mildly raised should be seen at two further visits before a decision about treatment is made. The timing of these follow-up visits is not crucial.
已知新发现血压升高的患者即使未经治疗,后续测量时血压也会降低。开展了一项研究,以确定(a)随访测量次数和(b)两次测量之间的间隔时长对这种血压下降的影响程度。在42家全科诊所中,110名患者首次被确定舒张压(第五期)大于90且小于110毫米汞柱。与首次测量相比,复诊时测量的舒张压和收缩压均明显降低。收缩压在首次和第二次就诊之间以及第二次和第三次就诊之间的间隔期明显下降。舒张压仅在首次和第二次就诊之间明显下降。就诊间隔时长与收缩压或舒张压的下降无关,但测量次数与之有关。这种血压下降模式不受患者年龄或性别的影响。根据这些结果,我们得出结论,在决定是否治疗之前,新发现血压轻度升高的患者应再进行两次复诊。这些随访就诊的时间并不关键。