Monro J L, Ross J K, Manners J M, Edwards J C, Lewis B, Hyde I, Ogilvie B C, Keeton B R, Conway N, Johnson A M
Br Med J (Clin Res Ed). 1983 Jan 29;286(6362):361-5. doi: 10.1136/bmj.286.6362.361.
The results of 3000 consecutive operations using cardio-pulmonary bypass show that the overall early mortality was 6.1%, dropping from 8.9% in the first 1000 to 4.4% in the third 1000. Operations for valve disease have been the most common, the early mortality for aortic valve replacement being 3.1% and for mitral valve replacement 2.9%. Combined aortic and mitral valve replacement had an early mortality of 4.4%. The number of patients undergoing isolated coronary artery bypass grafting has increased from 59 in the first 1000 to 292 in the third 1000 operations, with an overall early mortality of 1.3%. Six hundred and ninety seven patients underwent surgery for congenital heart disease with an overall early mortality of 10.9% (7.5% in the last 2000 cases). The patients have been followed up from one to 8.5 years. A high proportion have returned to work and enjoy a normal life. At the time of review, 87% of the 3000 patients were alive. Long waiting times for outpatient and inpatient care indicate underprovision of facilities relative to regional demand.
连续3000例体外循环手术的结果显示，总体早期死亡率为6.1%，从最初1000例的8.9%降至第3个1000例的4.4%。瓣膜疾病手术最为常见，主动脉瓣置换术的早期死亡率为3.1%，二尖瓣置换术为2.9%。主动脉瓣和二尖瓣联合置换术的早期死亡率为4.4%。接受单纯冠状动脉旁路移植术的患者数量从最初1000例中的59例增加到第3个1000例手术中的292例，总体早期死亡率为1.3%。697例患者接受了先天性心脏病手术，总体早期死亡率为10.9%（最近2000例病例中为7.5%）。患者随访时间为1至8.5年。很大一部分患者已重返工作岗位并过上正常生活。在复查时，3000例患者中有87%存活。门诊和住院治疗的长时间等待表明相对于地区需求，设施供应不足。
