Ingeberg S, Støckel M, Sørensen P J
Acta Haematol. 1983;69(4):243-8. doi: 10.1159/000206899.
Technetium-99m scintigraphy of the spleen was performed in 32 patients with various haematologic disorders prior to splenectomy. From the gamma camera image of the spleen, the weight of the spleen was estimated using two different mathematical formulas, and the results obtained were compared to the postoperative spleen weight. Both formulas revealed spleen weights showing highly significant correlations to the postoperative spleen weight and with similar standard deviations. Visual evaluation of the scintigram by an experienced examiner with classification of the spleens into four groups according to spleen weight revealed results as good as the mathematical calculations in predicting the postoperative spleen weight, both techniques giving diagnostic specificities of 0.70-0.80 for all groups and diagnostic sensitivities of 0.80-1.00. Physical examination of the abdomen showed that about 50% of the spleens weighing between 250 and 1,000 g were not palpable. Therefore, it is concluded that physical examination of the abdomen alone is unreliable. Radioisotope scintigraphy of the spleen is recommended, this method being fast, with negligible discomfort to the patient, and with sufficient accuracy for daily clinical work.
对32例患有各种血液系统疾病的患者在脾切除术前进行了锝-99m脾脏闪烁扫描。从脾脏的γ相机图像中，使用两种不同的数学公式估算脾脏重量，并将所得结果与术后脾脏重量进行比较。两种公式得出的脾脏重量与术后脾脏重量均显示出高度显著的相关性，且标准差相似。由经验丰富的检查人员对闪烁扫描图进行视觉评估，并根据脾脏重量将脾脏分为四组，结果显示在预测术后脾脏重量方面与数学计算效果相当，两种技术对所有组的诊断特异性为0.70 - 0.80，诊断敏感性为0.80 - 1.00。腹部体格检查显示，重量在250至1000克之间的脾脏约有50%无法触及。因此，得出结论，仅靠腹部体格检查是不可靠的。建议进行脾脏放射性核素闪烁扫描，该方法速度快，患者不适可忽略不计，且对于日常临床工作具有足够的准确性。
