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Binding of staphylococcal enterotoxin A (SEA) with human splenic lymphocytes.

作者信息

Ezepchuk Y u, Noskova V P, Aspetov R D, Novokhatsky A S, Noscov A N

出版信息

Int J Biochem. 1983;15(3):285-8. doi: 10.1016/0020-711x(83)90092-7.

DOI:10.1016/0020-711x(83)90092-7
PMID:6403393
Abstract
  1. The presence of specific binding of [125I]SEA with human splenocytes is established. 2. The association of toxin at 4 C is characterized by saturation, reversibility and a great affinity to a receptor (Kd = 4.0 x 10(-7) M). 3. The number of binding sites on a cell is equal to 6000. 4. At 23 C the binding of labelled toxin with a cell described by a biphasic curve. 5. Priming increases the association of SEA with the splenocytes and correspondingly increases the production level of gamma-interferon.
摘要

相似文献

1
Binding of staphylococcal enterotoxin A (SEA) with human splenic lymphocytes.
Int J Biochem. 1983;15(3):285-8. doi: 10.1016/0020-711x(83)90092-7.
2
Specific receptor binding of staphylococcal enterotoxins by murine splenic lymphocytes.鼠脾淋巴细胞对葡萄球菌肠毒素的特异性受体结合
Infect Immun. 1981 Sep;33(3):827-33. doi: 10.1128/iai.33.3.827-833.1981.
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Staphylococcal enterotoxin induced mitogenesis: toxin binding and cell-cell interactions.
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Bindings of toxic shock syndrome toxin-1 and staphylococcal enterotoxins A, B, and C to rabbit spleen cells.
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Superantigenic staphylococcal exotoxins induce T-cell proliferation in the presence of Langerhans cells or class II-bearing keratinocytes and stimulate keratinocytes to produce T-cell-activating cytokines.超抗原性葡萄球菌外毒素在朗格汉斯细胞或表达II类分子的角质形成细胞存在的情况下诱导T细胞增殖,并刺激角质形成细胞产生T细胞激活细胞因子。
J Invest Dermatol. 1994 Jan;102(1):31-8. doi: 10.1111/1523-1747.ep12371727.
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Receptors for toxic shock syndrome toxin-1 and staphylococcal enterotoxin A on human blood monocytes.人类血液单核细胞上的中毒性休克综合征毒素-1和葡萄球菌肠毒素A受体
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Membrane protein from rabbit T-lymphocytes, specifically binding staphylococcal enterotoxin A (SEA).来自兔T淋巴细胞的膜蛋白,特异性结合葡萄球菌肠毒素A(SEA)。
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[Formation of immune (gamma) interferon induced by staphylococcal enterotoxin and phytohemagglutinin].[由葡萄球菌肠毒素和植物血凝素诱导产生免疫(γ)干扰素]
Vopr Virusol. 1983 Jan-Feb;28(1):58-62.
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[Influence of staphylococcal enterotoxin A on immunogenicity of hepatocellular carcinoma cells].
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引用本文的文献

1
Binding and activation of major histocompatibility complex class II-deficient macrophages by staphylococcal exotoxins.葡萄球菌外毒素对主要组织相容性复合体II类缺陷巨噬细胞的结合与激活
Infect Immun. 1994 Sep;62(9):3907-15. doi: 10.1128/iai.62.9.3907-3915.1994.
2
Staphylococcal enterotoxins bind H-2Db molecules on macrophages.葡萄球菌肠毒素与巨噬细胞上的H-2Db分子结合。
Proc Natl Acad Sci U S A. 1995 Jul 3;92(14):6294-8. doi: 10.1073/pnas.92.14.6294.
3
Binding competition of toxic shock syndrome toxin 1 and other staphylococcal exoproteins for receptors on human peripheral blood mononuclear cells.
中毒性休克综合征毒素1及其他葡萄球菌外毒素与人外周血单核细胞表面受体的结合竞争
Infect Immun. 1990 Jul;58(7):2392-6. doi: 10.1128/iai.58.7.2392-2396.1990.