Pratt B M
J Exp Zool. 1983 Feb;225(2):329-35. doi: 10.1002/jez.1402250217.
Microphthalmic white (Miwh), when heterozygous, causes dilution of black fur to a uniform gray color. Miwh/+ also reduces the coloration of ear and tail skin. The present study, a quantitative assessment of the effects of Miwh/+ on cutaneous melanocytes, demonstrates that the primary effect of Miwh/+ on cutaneous pigmentation is to reduce the number of epidermal melanocytes. There is also indirect evidence that Miwh/+ reduces the rate of melanosome production within follicular melanocytes. These actions of Miwh/+ cause both lightened coloration of ear and tail skin and the deposition of fewer numbers of smaller melanosomes within the hair.
小眼白色（Miwh）基因杂合时，会使黑色皮毛变淡为均匀的灰色。Miwh/+ 还会使耳部和尾部皮肤的色素沉着减少。本研究对 Miwh/+ 对皮肤黑素细胞的影响进行了定量评估，结果表明 Miwh/+ 对皮肤色素沉着的主要作用是减少表皮黑素细胞的数量。也有间接证据表明 Miwh/+ 降低了毛囊黑素细胞内黑素小体的产生速率。Miwh/+ 的这些作用导致耳部和尾部皮肤颜色变浅，并且毛发内黑素小体数量减少且体积变小。
