Belghiti J, Goldfarb G, Gautero H, Fekete F, Boivin P
Surg Gynecol Obstet. 1983 Apr;156(4):489-92.
Bactericidal power of polymorphonuclear leukocytes was determined in eight patients with protein calorie malnutrition before and after nutritional therapy. Oxygen consumption associated with the uptake of zymosan particle by polymorphonuclear leukocytes, which is an exact reflection of the bactericidal power of leukocytes, was significantly decreased in untreated patients in the presence of both autologous and AB serum when compared with two control groups of eight normal patients. After nutritional therapy, oxygen consumption was found to be in the normal range in the presence of both autologous and AB serum. It is concluded that, in patients with protein calorie malnutrition, polymorphonuclear leukocytes have an intrinsic dysfunction, and this dysfunction is corrected after nutritional repletion.
在八名蛋白质热量营养不良患者接受营养治疗前后，测定了多形核白细胞的杀菌能力。多形核白细胞摄取酵母聚糖颗粒时的耗氧量能准确反映白细胞的杀菌能力，与两个由八名正常患者组成的对照组相比，未经治疗的患者在自身血清和AB血清存在的情况下，其耗氧量显著降低。营养治疗后，在自身血清和AB血清存在的情况下，耗氧量均在正常范围内。得出的结论是，蛋白质热量营养不良患者的多形核白细胞存在内在功能障碍，而这种功能障碍在营养补充后得到纠正。
