Navari R M, Carter J, Hillman R S
Acta Haematol. 1983;69(3):158-63. doi: 10.1159/000206882.
2 patients with premortem marrow necrosis in acute leukemia are discussed. A review of the course of each patient plus those in the literature suggests that premortem marrow necrosis may not be a poor prognostic sign in acute lymphoblastic leukemia but generally precedes a prolonged and fatal pancytopenia in acute myelogenous leukemia. The technetium-99m rhenium sulfur colloid marrow scan was found to be of value in assessing the extent and degree of necrosis of the marrow as well as in documenting and predicting marrow recovery following chemotherapy.
本文讨论了2例急性白血病患者生前骨髓坏死的情况。对每位患者以及文献中患者病程的回顾表明，生前骨髓坏死在急性淋巴细胞白血病中可能并非不良预后标志，但在急性髓细胞白血病中通常先于长期致命的全血细胞减少症出现。发现锝-99m铼硫胶体骨髓扫描在评估骨髓坏死的范围和程度以及记录和预测化疗后骨髓恢复方面具有价值。
