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一种在人体吸收和保留研究中使用超低剂量的59铁和65锌的全身计数技术。

A whole body counting technique using ultralow doses of 59Fe and 65Zn in absorption and retention studies in humans.

作者信息

Lykken G I

出版信息

Am J Clin Nutr. 1983 Apr;37(4):652-62. doi: 10.1093/ajcn/37.4.652.

Abstract

A whole body counting technique is described which allows monitoring of gamma ray emission rates from body levels of 59Fe and 65Zn in the same range as emission rates of gamma rays from naturally occurring 40K in the total body. Consequently absorption/retention studies were performed with doses of 0.1 microCi. Experimental results from studies using corn intrinsically labeled with 65Zn and wheat intrinsically labeled with 59Fe are presented and illustrate how absorption of 59Fe as low as 4% and retention of 65Zn up to 418 days were measured in humans.

摘要

本文描述了一种全身计数技术,该技术可监测人体中59Fe和65Zn的γ射线发射率,其范围与全身天然存在的40K的γ射线发射率相同。因此,使用了0.1微居里的剂量进行吸收/保留研究。文中展示了使用内源性标记65Zn的玉米和内源性标记59Fe的小麦进行研究的实验结果,这些结果说明了在人体中如何测量低至4%的59Fe吸收率和长达418天的65Zn保留率。

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