[使用两种免疫刺激剂及PFC试验研究免疫刺激从母体向幼鼠的传递]

[Study of the transfer of immunostimulation from the mother to the young mouse using 2 immunostimulants and the PFC test].

作者信息

Gendre F, Huart B, Binder P, Deschaux P, Fontanges R

出版信息

C R Seances Acad Sci III. 1983 Jan 10;296(1):15-8.

Abstract

Pregnant Mice were stimulated with two substances, an antibronchitic lysate (LAB) and diethyldithiocarbamate (DTC). PFC response was studied in mothers and their offspring for 6 weeks after birth. An increase in PFC response was noted in the immunostimulated adult Mice. In the newborn Mice, the number of PFC increased between the 1st and 6th week. In comparison with controls, PFC response appeared later in the newborns to LAB-stimulated mothers and earlier in those to DTC-stimulated mothers.

摘要

用两种物质，即抗支气管炎裂解物（LAB）和二乙基二硫代氨基甲酸盐（DTC）刺激怀孕小鼠。在出生后6周内研究了母亲及其后代的PFC反应。在免疫刺激的成年小鼠中观察到PFC反应增加。在新生小鼠中，PFC的数量在第1周和第6周之间增加。与对照组相比，新生小鼠对LAB刺激的母亲的PFC反应出现较晚，而对DTC刺激的母亲的PFC反应出现较早。