Foord K D, Morcos S K, Ward P
Clin Radiol. 1983 May;34(3):309-12. doi: 10.1016/s0009-9260(83)80345-6.
Three preparations, two based on magnesium citrate and one an optimised oral mannitol regime, have been compared for their effectiveness in clearing the large bowel prior to double-contrast barium enema and for effects on barium mucosal coating. If excellent clearance alone is taken as the criterion of acceptability, the preparations based on magnesium citrate are shown to be equal to each other, but better than mannitol. No significant difference in coating performance is seen between the three preparations. Magnesium citrate regimes cause significantly less nausea and vomiting than mannitol. No differences are noted in the frequency of abdominal or rectal pain between the preparations. It is concluded that mannitol should be abandoned as a barium enema preparation.
对三种肠道准备方法进行了比较，其中两种基于枸橼酸镁，一种是优化的口服甘露醇方案，比较它们在双重对比钡灌肠前清洁大肠的效果以及对钡剂黏膜涂层的影响。如果仅以出色的清洁效果作为可接受的标准，基于枸橼酸镁的制剂效果相当，但优于甘露醇。三种制剂在涂层性能上没有显著差异。枸橼酸镁方案引起的恶心和呕吐明显少于甘露醇。各制剂在腹部或直肠疼痛的发生率上没有差异。结论是甘露醇应不再作为钡灌肠的肠道准备药物。
