Anjaria K B, Madhvanath U
Mutat Res. 1983 May;120(2-3):111-9. doi: 10.1016/0165-7992(83)90151-3.
The interaction between the mutagenic action of chemicals and radiation was studied by using a diploid yeast strain Saccharomyces cerevisiae BZ 34 with mitotic gene conversion as the end-point. The cells were treated with EMS, MMS or 4-NQO alone or in combination with gamma-radiation. The 2 alkylating agents EMS and MMS produced an additive mutagenic response, whereas 4-NQO exhibited an antagonistic effect in the combined treatment with gamma-radiation.
通过使用以有丝分裂基因转换为终点的二倍体酵母菌株酿酒酵母BZ 34，研究了化学物质和辐射的诱变作用之间的相互作用。细胞分别用EMS、MMS或4-NQO单独处理，或与γ辐射联合处理。两种烷化剂EMS和MMS产生了累加诱变反应，而4-NQO在与γ辐射联合处理时表现出拮抗作用。
