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静脉注射酒精对眼球扫视运动及醉酒主观评价的急性影响。

Acute effects of intravenously given alcohol on saccadic eye movements and subjective evaluations of intoxication.

作者信息

Jäntti V, Lang A H, Keskinen E, Lehtinen I, Pakkanen A

出版信息

Psychopharmacology (Berl). 1983;79(2-3):251-5. doi: 10.1007/BF00427822.

DOI:10.1007/BF00427822
PMID:6405437
Abstract

Effects of intravenously given alcohol on eye movements were analysed in ten voluntary subjects. Each subject served as his/her own control. Good correlations were found between the changes in saccade variables and subjective evaluations of alertness, eye movement control and intoxication. Interindividually, the subjective evaluation of drunkenness correlates with the alcohol effect on saccade variables better than do the other subjective variables or blood or breath alcohol concentrations. A steady decrease of mean and maximum velocity and a steady increase in the duration of saccades was observed during the alcohol infusion. The latency of saccades also increased. There was, however, a slight decrease of latency due to alcohol 15 min after the start of infusion, suggesting a biphasic effect of alcohol on saccade latency.

摘要

在10名自愿受试者中分析了静脉注射酒精对眼动的影响。每个受试者都作为自己的对照。扫视变量的变化与警觉性、眼动控制和醉酒程度的主观评价之间存在良好的相关性。个体间,醉酒的主观评价与酒精对扫视变量的影响之间的相关性比其他主观变量或血液或呼气酒精浓度更好。在酒精输注期间,观察到平均速度和最大速度稳步下降,扫视持续时间稳步增加。扫视潜伏期也增加。然而,在输注开始15分钟后,酒精导致潜伏期略有下降,表明酒精对扫视潜伏期有双相作用。

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