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眼跳运动分析作为一种衡量药物对人类心理运动表现影响的方法。

Saccadic eye movement analysis as a measure of drug effects on human psychomotor performance.

作者信息

Griffiths A N, Marshall R W, Richens A

出版信息

Br J Clin Pharmacol. 1984;18 Suppl 1(Suppl 1):73S-82S. doi: 10.1111/j.1365-2125.1984.tb02584.x.

Abstract

Analysis of human horizontal saccadic eye movements can provide measurements of central nervous system depression and stimulation. Effects on saccadic eye movements have been observed in normal volunteers with barbiturates, benzodiazepines, opiates and related compounds, carbamazepine, amphetamine and ethanol. A suite of programmes have been developed to allow the generation, collection and analysis of saccadic eye movements using a CBM 3032, 8032 or BBC B microcomputer. The system allows almost continuous sampling and rapid analysis of movements.

摘要

对人类水平扫视眼动的分析能够提供中枢神经系统抑制和兴奋的测量数据。在正常志愿者中,已观察到巴比妥类药物、苯二氮卓类药物、阿片类及相关化合物、卡马西平、苯丙胺和乙醇对扫视眼动的影响。现已开发出一套程序,以便使用CBM 3032、8032或BBC B微型计算机生成、收集和分析扫视眼动。该系统允许对眼动进行几乎连续的采样和快速分析。

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