Paul E, Graef V, Ruppel R, Hellwich M
Z Hautkr. 1983 Feb 15;58(4):262-5.
In case of uncharacteristic patient complaints or slightly pathologic BSR or liver enzyme levels in patients, suffering from melanoma, the determination of 5-S-cysteinyldopa in the 24-h-urine may be of great diagnostic value. If the complaints and the pathologic values are early symptoms and signs of generalized metastases being clinically not yet manifest, the excretion of 5-S-cysteinyldopa in the urine is often increased. In such cases, a thorough and possibly invasive search for metastases is indicated.
对于患有黑色素瘤的患者,若出现非典型的患者主诉或轻微异常的基础血清反应(BSR)或肝酶水平,测定24小时尿液中的5-S-半胱氨酰多巴可能具有重要的诊断价值。如果这些主诉和异常值是尚未在临床上显现的全身转移的早期症状和体征,尿液中5-S-半胱氨酰多巴的排泄量通常会增加。在这种情况下,需要进行全面且可能具有侵入性的转移灶排查。