黑色素瘤患者尿液中的5-S-半胱氨酰多巴
5-S-cysteinyldopa in the urine of melanoma patients.
作者信息
Agrup G, Agrup P, Andersson T, Falck B, Hansson J A, Jacobsson S, Rorsman H, Rosengren E, Rosengren A M
出版信息
Acta Derm Venereol. 1977;57(2):113-6.
PMID:71802
Abstract
A newly discovered amino acid, 5-S-cysteinyldopa, present in the urine of healthy subjects is excreted in pathological amounts in many patients suffering from melanoma metastases. Increased excretion of 5-S-cysteinyldopa may be observed before metastases become clinically evident. Determination of 5-S-cysteinyldopa is superior to determination of dopa+dopamine in the diagnosis of melanoma metastases.
摘要
一种新发现的氨基酸，5-S-半胱氨酰多巴，存在于健康受试者的尿液中，而在许多患有黑色素瘤转移的患者中，其排泄量呈病理性增加。在转移灶出现临床症状之前，就可能观察到5-S-半胱氨酰多巴排泄量的增加。在黑色素瘤转移的诊断中，测定5-S-半胱氨酰多巴优于测定多巴+多巴胺。
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