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[间脑疾病的诊断。蝶鞍区及间脑肿瘤手术前后间脑疾病诊断的临床研究]

[Diagnosis of diencephalic disorders. Clinical study on the diagnosis of diencephalic disorders before and after surgery of tumors in the region of the sella and the diencephalon].

作者信息

Clar H E

出版信息

Fortschr Med. 1978 Apr 13;96(14):749-54.

PMID:640558
Abstract

The clinical symptomatology of diencephalic disorders is studied in 193 patients operated because of tumors in the sellar region. A new classification of these tumors is established according to the localization and degree of compression of the hypothalamus. The following parameters were examined: body temperature, blood pressure, pulse rate, electrolytes, fluid balance, and serum glucose. In addition, hormonal tests for hypophyseal and diencephalic disorders were carried out. The analysis shows a significant postoperative temperature rise in patients with tumors in the hypothalamic region, depending on the degree of compression of the hypothalamus. There is no relation to histological findings or form of operative approach. Postoperative diabetes insipidus as well as endocrine diencephalic disorders correlate also with the degree of diencephalic lesion. The same results were found with glucose regulation. In contrast, blood pressure, pulse rate, and electrolytes show no differences in the groups tested.

摘要

对193例因鞍区肿瘤而接受手术的患者的间脑疾病临床症状进行了研究。根据下丘脑的定位和受压程度建立了这些肿瘤的新分类。检查了以下参数:体温、血压、脉搏率、电解质、液体平衡和血糖。此外,还对垂体和间脑疾病进行了激素检测。分析表明,下丘脑区域肿瘤患者术后体温显著升高,这取决于下丘脑的受压程度。与组织学结果或手术入路形式无关。术后尿崩症以及间脑内分泌紊乱也与间脑病变程度相关。在血糖调节方面也发现了相同的结果。相比之下,血压、脉搏率和电解质在测试组中没有差异。

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