Butenandt O
Fortschr Med. 1983 Apr 21;101(15):667-9.
Euthyroid or hypothyroid goitre in childhood is due to hyperstimulation by TSH in iodine deficiency or inborn errors of thyroid hormone synthesis. Hyperthyroid goitre results from presence of LATS. Hashimoto's strumitis may be hypo- or hyperthyroid. Therapy consists of iodine, thyroxine in hypothyroid goitres or in thyrostatic suppression in hyperthyroid goitres. Whereas hypothyroidism requests lifelong therapy, hyperthyroidism requires therapy for 1 to 2 years if successful. Otherwise, operative procedures are necessary.
儿童期的甲状腺功能正常或减退性甲状腺肿是由于碘缺乏或甲状腺激素合成的先天性缺陷中促甲状腺激素(TSH)过度刺激所致。甲状腺功能亢进性甲状腺肿是由长效甲状腺刺激素(LATS)的存在引起的。桥本甲状腺炎可能导致甲状腺功能减退或亢进。治疗方法包括补充碘、对甲状腺功能减退性甲状腺肿使用甲状腺素或对甲状腺功能亢进性甲状腺肿进行甲状腺抑制治疗。甲状腺功能减退需要终身治疗,而甲状腺功能亢进如果治疗成功则需要1至2年的治疗。否则,就需要进行手术。