Mehta N B
J Clin Psychiatry. 1983 May;44(5 Pt 2):56-9.
The chemical structure and synthesis of bupropion are described and compared with typical polycyclic antidepressants to point up the novelty and simplicity of this drug. The features of bupropion's substructure are discussed to help in understanding the observed pharmacological differences among bupropion, tricyclic antidepressants, and psychostimulants.
描述了安非他酮的化学结构与合成,并将其与典型的多环抗抑郁药进行比较,以突出该药物的新颖性与简易性。讨论了安非他酮子结构的特征,以助于理解安非他酮、三环类抗抑郁药及精神兴奋药之间观察到的药理学差异。