Ewing D
Radiat Res. 1983 Apr;94(1):171-89.
The anoxic sensitization of bacterial spores by added H2O2 has been studied. Two mechanistic pathways for damage from H2O2 were found; one of these requires the presence of OH radicals. For this kind of damage, the relationship between H2O2 and OH appears to be that they are reactants. O-2 (and/or HO2), the product of such a reaction, is likely the agent which actually causes damage. These results with reagent H2O2 are compared with results of experiments in which H2O2 and OH are present as radiolytic products.
已对添加过氧化氢（H₂O₂）使细菌孢子产生缺氧致敏作用进行了研究。发现了过氧化氢造成损伤的两种作用机制途径；其中一种需要羟基自由基（OH）的存在。对于这种损伤，过氧化氢与羟基自由基之间的关系似乎是它们作为反应物。这种反应的产物超氧阴离子（O₂⁻）（和/或过氧化氢自由基（HO₂））可能是实际造成损伤的介质。将这些使用试剂过氧化氢的结果与过氧化氢和羟基自由基作为辐射分解产物存在的实验结果进行了比较。
