Clémenty J, Delpech M C, Mazeau C, Stingre P, Bricaud H
Arch Mal Coeur Vaiss. 1983 Feb;76 Spec No:55-67.
Evaluating the cost of coronary artery disease is difficult because it must take into account not only the cost of the disease process itself, but also that of prevention and research. 1. The cost of the disease process itself may be assessed by: a) an analytical study of the real cost of diagnostic and therapeutic procedures; b) a synthetic study of the procedures according to the clinical forms of the disease. Although this task is simple for a given patient, extrapolation of the results to a whole group of patients is more aleatory; c) an epidemiological study of the different forms of coronary artery disease: although global data is available the absence of a coronary artery disease register makes this a difficult problem; d) an evaluation of the socio-professional repercussions of coronary artery disease with integration of the cost and loss in gross national product. 2 The cost of prevention can be assessed by taking the following factors into consideration: a) cost of individual primary prevention which poses the problems of check-up examinations; b) cost of community primary prevention; c) cost of research including fundamental research on the atheromatous process and myocardial ischemia plus clinical research such as secondary prevention enquiries. In conclusion, it appears that: --it is difficult to determine the cost of coronary artery disease without a specialist register; --the cost of coronary artery disease should be considered from positive (source of economic activity) and negative points of view (socio-professional repercussions); --a reduction in the cost of coronary artery disease requires a deeper understanding of the disease, better prophylaxis and socio-professional rehabilitation, and improved organisation of exciting health structures.
评估冠状动脉疾病的成本很困难,因为这不仅必须考虑疾病过程本身的成本,还需考虑预防和研究的成本。1. 疾病过程本身的成本可通过以下方式评估:a) 对诊断和治疗程序的实际成本进行分析研究;b) 根据疾病的临床形式对这些程序进行综合研究。尽管对于某一特定患者而言这项任务很简单,但将结果外推至整个患者群体则更具随机性;c) 对冠状动脉疾病的不同形式进行流行病学研究:尽管有总体数据,但缺乏冠状动脉疾病登记使得这成为一个难题;d) 评估冠状动脉疾病对社会职业的影响,并综合考虑国民生产总值中的成本和损失。2. 预防成本可通过考虑以下因素进行评估:a) 个体一级预防的成本,这带来了体检检查的问题;b) 社区一级预防的成本;c) 研究成本,包括对动脉粥样硬化过程和心肌缺血的基础研究,以及诸如二级预防调查等临床研究。总之,似乎:——没有专科登记就难以确定冠状动脉疾病的成本;——冠状动脉疾病的成本应从积极(经济活动来源)和消极(社会职业影响)两个角度来考虑;——降低冠状动脉疾病的成本需要更深入地了解该疾病、更好的预防和社会职业康复措施,以及改善现有卫生机构的组织架构。