乳糖酶活性在成年大鼠肠道中受激素控制。
Lactase activity is under hormonal control in the intestine of adult rat.
作者信息
Raul F, Noriega R, Nsi-Emvo E, Doffoel M, Grenier J F
出版信息
Gut. 1983 Jul;24(7):648-52. doi: 10.1136/gut.24.7.648.
Abstract
In the adult rat, starvation during 48 hours led to a three fold increase of lactase specific activity in the intestinal brush border membranes. Thyroxine injection during the three days before death (0.5 micrograms/g daily) inhibited the stimulation of lactase activity induced by starvation without modifying sucrase activity whereas hydrocortisone injections (25 micrograms/g daily) or thyroidectomy did not modify the stimulatory effect of starvation on lactase activity. These results suggests a specific hormonal control of intestinal lactase activity in the rat.
摘要
在成年大鼠中，48小时的饥饿导致肠刷状缘膜中乳糖酶比活性增加了三倍。在死亡前三天每天注射甲状腺素（0.5微克/克）可抑制饥饿诱导的乳糖酶活性刺激，而不改变蔗糖酶活性，而每天注射氢化可的松（25微克/克）或甲状腺切除则不会改变饥饿对乳糖酶活性的刺激作用。这些结果表明大鼠肠道乳糖酶活性存在特定的激素调控。
相似文献
1
Lactase activity is under hormonal control in the intestine of adult rat.乳糖酶活性在成年大鼠肠道中受激素控制。
Gut. 1983 Jul;24(7):648-52. doi: 10.1136/gut.24.7.648.
2
Modulation by thyroxine of the amount of lactase protein in the jejunum of adult rats.甲状腺素对成年大鼠空肠乳糖酶蛋白含量的调节作用。
Enzyme. 1986;36(3):216-20. doi: 10.1159/000469295.
3
Different effect of starvation on activity of sucrase and lactase in rat jejunoileum.饥饿对大鼠空肠回肠中蔗糖酶和乳糖酶活性的不同影响。
Am J Physiol. 1983 Apr;244(4):G449-55. doi: 10.1152/ajpgi.1983.244.4.G449.
4
Stimulation of disaccharidase activities in the jejunal brush border membrane of adult rat by total parenteral nutrition. Effects of thyroid hormones.全胃肠外营养对成年大鼠空肠刷状缘膜双糖酶活性的刺激作用。甲状腺激素的影响。
Digestion. 1984;29(3):190-6. doi: 10.1159/000199030.
5
Demonstration of a difference in expression of maximal lactase and sucrase activity along the villus in the adult rat jejunum.成年大鼠空肠绒毛不同部位乳糖酶和蔗糖酶最大活性表达差异的证实。
Gastroenterology. 1980 Sep;79(3):503-7. doi: 10.1016/0016-5085(80)90375-3.
6
Thyroxine-evoked decrease of jejunal lactase activity in adult rats.甲状腺素引起成年大鼠空肠乳糖酶活性降低。
Gastroenterology. 1977 Aug;73(2):425-7.
7
Sequential disaccharidase loss in rat intestinal blind loops: impact of malnutrition.大鼠肠道盲袢中双糖酶的顺序性丧失：营养不良的影响
Am J Physiol. 1985 Jun;248(6 Pt 1):G626-32. doi: 10.1152/ajpgi.1985.248.6.G626.
8
Thyroxine and cortisone cooperate to modulate postnatal intestinal enzyme differentiation in the rat.甲状腺素和可的松协同调节大鼠出生后肠道酶的分化。
Am J Physiol. 1991 Mar;260(3 Pt 1):G371-8. doi: 10.1152/ajpgi.1991.260.3.G371.
9
Effects of starvation and refeeding on jejunal disaccharidase activity.饥饿和再喂养对空肠双糖酶活性的影响。
Dig Dis Sci. 1992 Jun;37(6):827-32. doi: 10.1007/BF01300379.
10
引用本文的文献
1
Conditioned taste aversion versus avoidance: A re-examination of the separate processes hypothesis.条件性味觉厌恶与回避：对分离过程假设的再检验。
PLoS One. 2019 Jun 19;14(6):e0217458. doi: 10.1371/journal.pone.0217458. eCollection 2019.
2
Effect of triiodothyronine on the growth and survival of larval striped bass (Morone saxatilis).三碘甲状腺原氨酸对幼期条纹鲈（Morone saxatilis）生长和存活的影响。
Fish Physiol Biochem. 1996 Feb;15(1):57-64. doi: 10.1007/BF01874838.
3
Gestational diabetes affects postnatal development of transport and enzyme functions in rat intestine.妊娠糖尿病影响大鼠肠内转运和酶功能的产后发育。
Mol Cell Biochem. 2012 Feb;361(1-2):71-7. doi: 10.1007/s11010-011-1090-0. Epub 2011 Oct 2.
4
Hormone induced expression of brush border lactase in suckling rat intestine.激素诱导哺乳期大鼠肠道刷状缘乳糖酶的表达。
Mol Cell Biochem. 2008 May;312(1-2):11-6. doi: 10.1007/s11010-008-9715-7. Epub 2008 Feb 14.
5
Dietary induced increase of lactase activity in adult rats is independent of adrenals.饮食诱导成年大鼠乳糖酶活性增加与肾上腺无关。
Experientia. 1984 Nov 15;40(11):1287-8. doi: 10.1007/BF01946678.
6
Adaptation of intestinal enzymes to seasonal and dietary changes in a hibernator: the European hamster (Cricetus cricetus).冬眠动物欧洲仓鼠（Cricetus cricetus）肠道酶对季节和饮食变化的适应性
J Comp Physiol B. 1988;158(2):143-9. doi: 10.1007/BF01075827.
7
Effect of chronic ethanol intake on lactase activity and active galactose absorption in rat small intestine.慢性乙醇摄入对大鼠小肠乳糖酶活性及活性半乳糖吸收的影响。
Gut. 1987 Jan;28(1):56-60. doi: 10.1136/gut.28.1.56.
8
Thyroid hormone effects on lactase expression by rat enterocytes.甲状腺激素对大鼠肠上皮细胞乳糖酶表达的影响。
J Physiol. 1986 Jul;376:253-65. doi: 10.1113/jphysiol.1986.sp016152.
9
Reversibility of spermine-induced intestinal maturation in the rat.精胺诱导的大鼠肠道成熟的可逆性
Dig Dis Sci. 1990 Dec;35(12):1528-36. doi: 10.1007/BF01540571.
10
Specific expression of lactase in the jejunum and colon during postnatal development and hormone treatments in the rat.大鼠出生后发育过程中乳糖酶在空肠和结肠中的特异性表达及激素处理
Biochem J. 1990 May 15;268(1):99-103. doi: 10.1042/bj2680099.
本文引用的文献
1
Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
J Biol Chem. 1951 Nov;193(1):265-75.
2
INTESTINAL DISACCHARIDASE ACTIVITIES IN ADULT AND SUCKLING RATS.成年和乳鼠的肠道双糖酶活性
Biochim Biophys Acta. 1964 Nov 22;92:305-11. doi: 10.1016/0926-6569(64)90187-7.
3
[ADAPTATION OF THE INTESTINAL LACTASE TO THE ADMINISTRATION OF LACTOSE IN THE ADULT RAT].[成年大鼠肠道乳糖酶对乳糖摄入的适应性]
Helv Physiol Pharmacol Acta. 1964;22:7-14.
4
Studies of small intestine during development. I. Distribution and activity of beta-galactosidase.发育过程中小肠的研究。I. β-半乳糖苷酶的分布与活性。
Biochim Biophys Acta. 1962 Aug 13;62:353-62. doi: 10.1016/0006-3002(62)90097-5.
5
Modifications of brush border enzyme activities during starvation in the jejunum and ileum of adult rats.成年大鼠空肠和回肠饥饿期间刷状缘酶活性的变化
Enzyme. 1982;28(4):328-35. doi: 10.1159/000459119.
6
Effects of prolonged alcohol administration and a high carbohydrate-low protein diet on the activities of the jejunal brush border enzymes in the rat.长期给予酒精及高碳水化合物-低蛋白饮食对大鼠空肠刷状缘酶活性的影响。
Gut. 1982 Nov;23(11):962-7. doi: 10.1136/gut.23.11.962.
7
Early changes in brush border disaccharidase kinetics in rat jejunum following subcutaneous administration of tetraiodothyronine: a quantitative histochemical study on villi revealing normal morphology.皮下注射甲状腺素后大鼠空肠刷状缘双糖酶动力学的早期变化：绒毛定量组织化学研究显示形态正常
Histochemistry. 1981;73(1):151-60. doi: 10.1007/BF00493141.
8
Dietary-induced rapid increase of rat jejunal sucrase and lactase activity in all regions of the villus.饮食诱导大鼠空肠蔗糖酶和乳糖酶活性在绒毛所有区域迅速增加。
FEBS Lett. 1981 Jun 29;129(1):89-92. doi: 10.1016/0014-5793(81)80762-4.
9
Increased activity of rat intestinal lactase due to increased intake of alpha-saccharides (starch, sucrose) in isocaloric diets.在等热量饮食中，由于α-糖类（淀粉、蔗糖）摄入量增加，大鼠肠道乳糖酶活性增强。
J Nutr. 1981 Jun;111(6):943-53. doi: 10.1093/jn/111.6.943.
10
Effect of sucrose refeeding on disaccharidase and aminopeptidase activities of intestinal villus and crypt cells in adult rats. Evidence for a sucrose-dependent induction of sucrase in the crypt cells.蔗糖再喂养对成年大鼠肠绒毛和隐窝细胞双糖酶及氨肽酶活性的影响。隐窝细胞中蔗糖酶的蔗糖依赖性诱导的证据。
Biochim Biophys Acta. 1980 Jun 5;630(1):1-9. doi: 10.1016/0304-4165(80)90130-0.
Zotero 插件