Colleen S, Luttropp W, Mårdh P A, Ripa T
Invest Urol. 1978 Mar;15(5):367-71.
Recurrent urinary tract infections are known to occur among 5 per cent of all females. These women frequently have episodes of symptoms of lower urinary tract infection even between periods of bacteriuria. In the present study, 25 women with a history of recurrent urinary tract infections, found to lack signs of obstructive uropathy, were subjected to an extensive urological and microbiological survey. The investigation showed that (i) "pyuria" was common (9/12) but usually of urethral origin, (ii) introital and/or urethral colonization with Enterobacteriaceae often (11/25) occurred, (iii) apart from Escherichia coli found in three patients, a Bacteroides species was isolated in two and ureaplasmas in one patient from suprapubically aspirated urine, and (iv) chlamydia, gonococci, and trichomonads were not found. The patients were given methenaminehippurate for 1 week and then reexamined. The treatment did not seem to influence the indigenous flora of the lower urogenital tract.
已知5%的女性会反复发生尿路感染。这些女性即使在无细菌尿的时期也经常出现下尿路感染的症状。在本研究中，对25名有反复尿路感染病史且无梗阻性尿路病体征的女性进行了广泛的泌尿外科和微生物学检查。调查显示：（i）“脓尿”很常见（9/12），但通常起源于尿道；（ii）肠杆菌科常在阴道入口和/或尿道定植（11/25）；（iii）除3例患者中发现大肠杆菌外，从耻骨上抽吸的尿液中，2例分离出拟杆菌属，1例分离出脲原体；（iv）未发现衣原体、淋球菌和滴虫。患者接受了1周的马尿酸乌洛托品治疗，然后再次进行检查。该治疗似乎并未影响下泌尿生殖道的固有菌群。
