绢毛猴感染人非甲非乙型肝炎病毒的实验研究。

Experimental infection of Tamarins with human non-A, non-B hepatitis virus.

作者信息

Karayiannis P, Scheuer P J, Bamber M, Cohn D, Hurn B A, Thomas H C

出版信息

J Med Virol. 1983;11(3):251-6. doi: 10.1002/jmv.1890110308.

Abstract

Non-A, non-B (NANB) viral hepatitis was successfully transmitted to two colony-born Tamarins following inoculation with antihaemophilic factor VIII concentrate or the "H" inoculum. Both animals showed histological and ultrastructural evidence of viral hepatitis, with raised alanine aminotransferase (ALT) levels from the second week after inoculation through to the end of follow-up, 5 months later.

摘要

在给两只圈养出生的绢毛猴接种抗血友病因子VIII浓缩物或“H”接种物后，成功将非甲非乙型（NANB）病毒性肝炎传播给了它们。两只动物均显示出病毒性肝炎的组织学和超微结构证据，从接种后第二周直至5个月后的随访结束，丙氨酸转氨酶（ALT）水平均升高。