锂疗法对肾小球滤过率的影响。

Effect of lithium therapy on glomerular filtration rate.

作者信息

Decina P, Oliver J A, Sciacca R R, Colt E, Fieve R R

出版信息

Am J Psychiatry. 1983 Aug;140(8):1065-7. doi: 10.1176/ajp.140.8.1065.

DOI:10.1176/ajp.140.8.1065

Abstract

Patients taking lithium had a slightly higher serum creatinine concentration than controls. Creatinine concentration was independent of lithium level or therapy length, suggesting that lithium decreases glomerular filtration but that this effect is small, noncumulative, and of marginal clinical significance.

摘要

服用锂盐的患者血清肌酐浓度略高于对照组。肌酐浓度与锂盐水平或治疗时长无关，这表明锂盐会降低肾小球滤过率，但这种影响较小、无累积效应且临床意义不大。