Gin H, Larnaudie B, Aubertin J
Br Med J (Clin Res Ed). 1983 Jul 23;287(6387):249-50. doi: 10.1136/bmj.287.6387.249.
An elderly woman with longstanding insulin dependent diabetes tried to commit suicide by injecting 400 units of insulin subcutaneously (usual total daily dose 56 units). She was admitted to hospital within the hour and treated with the aid of an artificial pancreas. This avoided the usual difficulty of the physician having to cope with rapid and substantial fluctuations in blood glucose concentrations and 67 hours after the overdose insulin was reinstituted. Using an artificial pancreas in insulin overdose is an important advance in management and may avoid the need for surgical intervention such as excising the site of injection.
一位患有长期胰岛素依赖型糖尿病的老年女性试图通过皮下注射400单位胰岛素自杀(通常每日总剂量为56单位)。她在一小时内被送往医院,并借助人工胰腺进行治疗。这避免了医生通常面临的应对血糖浓度快速大幅波动的困难,并且在过量注射胰岛素67小时后重新开始使用胰岛素。在胰岛素过量时使用人工胰腺是管理方面的一项重要进展,可能避免诸如切除注射部位等外科干预的需要。