Smith J E, Mahaffey E, Board P
J Am Vet Med Assoc. 1978 Mar 15;172(6):701-3.
A solution consisting of ascorbate phosphate, citric acid, sodium citrate, sodium phosphate, and dextrose was developed to extend the shelf life of canine blood stored for transfusion. The 24-hour poststorage viability remained above 70% for 6 weeks of storage at 4 C. The concentration of 2,3 diphosphoglycerate remained constant for 3 weeks, then declined slowly. After 6 weeks of storage, the 2,3 diphosphoglycerate content was still sufficiently high to allow adequate dissociation of oxygen from oxyhemoglobin in vivo. It was concluded that blood stored up to 6 weeks in this solution would be safe to use for transfusion.
一种由抗坏血酸磷酸盐、柠檬酸、柠檬酸钠、磷酸钠和葡萄糖组成的溶液被研发出来，用于延长储存以备输血的犬类血液的保质期。在4℃储存6周后，储存24小时后的存活率仍保持在70%以上。2,3-二磷酸甘油酸的浓度在3周内保持恒定，然后缓慢下降。储存6周后，2,3-二磷酸甘油酸的含量仍然足够高，足以在体内使氧从氧合血红蛋白中充分解离。得出的结论是，在这种溶液中储存长达6周的血液用于输血是安全的。
