Barreca T, Rossi B, Magnani G, Sartucci F, Arena R, Rolandi E
Clin Endocrinol (Oxf). 1983 Apr;18(4):319-25. doi: 10.1111/j.1365-2265.1983.tb00575.x.
The nyctohemeral pattern of serum luteinizing (LH), follicle-stimulating hormone (FSH) and prolactin (PRL) in eight patients with myotonic dystrophy (MD) was studied. Gonadotropin patterns were classified as adult, pubertal or infantile. Six patients showed an adult pattern, whereas two had a pubertal or infantile pattern. A normal pattern of PRL secretion was found in seven patients and a blunted sleep-related hormonal increase was observed in one. Impaired hypothalamic control of pituitary secretion in MD is proposed as the cause for these findings.
对8例强直性肌营养不良（MD）患者血清促黄体生成素（LH）、促卵泡激素（FSH）和催乳素（PRL）的昼夜节律模式进行了研究。促性腺激素模式分为成人型、青春期型或婴儿型。6例患者表现为成人型，而2例为青春期型或婴儿型。7例患者PRL分泌模式正常，1例观察到与睡眠相关的激素升高减弱。这些发现的原因被认为是MD患者下丘脑对垂体分泌的控制受损。
