Lox C D, Dorsett M M, Hampton R M
Clin Exp Hypertens B. 1983;2(2):179-90. doi: 10.3109/10641958309006078.
Patients with documented pre-eclampsia of pregnancy were utilized on this study. Various clotting factor activities were measured and these included the prothrombin time (PT), partial thromboplastin time (APTT), fibrinogen (FIB), and clotting factors II, V, VII, VIII, X and XII plus the platelets. Statistical analysis of the data indicates that the activity of many clotting factors was significantly changed due to pre-eclampsia, in general, being elevated over normal pregnant controls. This was primarily reflected in the common pathway portion of the clotting cascade.
本研究纳入了有子痫前期妊娠记录的患者。测量了各种凝血因子活性，这些包括凝血酶原时间（PT）、活化部分凝血活酶时间（APTT）、纤维蛋白原（FIB）以及凝血因子II、V、VII、VIII、X和XII加上血小板。数据的统计分析表明，许多凝血因子的活性因子痫前期而发生显著变化，总体上高于正常妊娠对照组。这主要反映在凝血级联反应的共同途径部分。
