镁、氧化应激、炎症与心血管疾病
Magnesium, Oxidative Stress, Inflammation, and Cardiovascular Disease.
作者信息
Liu Man, Dudley Samuel C
机构信息
Division of Cardiology, Department of Medicine, the Lillehei Heart Institute, University of Minnesota at Twin Cities, Minneapolis, MN 55455, USA.
出版信息
Antioxidants (Basel). 2020 Sep 23;9(10):907. doi: 10.3390/antiox9100907.
Hypomagnesemia is commonly observed in heart failure, diabetes mellitus, hypertension, and cardiovascular diseases. Low serum magnesium (Mg) is a predictor for cardiovascular and all-cause mortality and treating Mg deficiency may help prevent cardiovascular disease. In this review, we discuss the possible mechanisms by which Mg deficiency plays detrimental roles in cardiovascular diseases and review the results of clinical trials of Mg supplementation for heart failure, arrhythmias and other cardiovascular diseases.
低镁血症常见于心力衰竭、糖尿病、高血压和心血管疾病中。血清镁（Mg）水平低是心血管疾病和全因死亡率的一个预测指标，治疗镁缺乏可能有助于预防心血管疾病。在本综述中，我们讨论了镁缺乏在心血管疾病中发挥有害作用的可能机制，并回顾了补充镁对心力衰竭、心律失常和其他心血管疾病的临床试验结果。
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