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再次接触苯妥英后发生致命性中毒性表皮坏死松解症：一例报告

Fatal toxic epidermal necrolysis following reexposure to phenytoin: a case report.

作者信息

Schmidt D, Kluge W

出版信息

Epilepsia. 1983 Aug;24(4):440-3. doi: 10.1111/j.1528-1157.1983.tb04914.x.

DOI:10.1111/j.1528-1157.1983.tb04914.x
PMID:6409601
Abstract

A 66-year-old epileptic patient developed toxic epidermal necrolysis following an oral loading dose of phenytoin. Administration of the drug was discontinued and the patient survived. Two years later he inadvertently received phenytoin again. The reexposure to phenytoin led to a fatal toxic epidermal necrolysis.

摘要

一名66岁的癫痫患者在口服负荷剂量的苯妥英钠后发生中毒性表皮坏死松解症。药物停用后患者存活。两年后，他意外再次服用苯妥英钠。再次接触苯妥英钠导致了致命的中毒性表皮坏死松解症。

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[Stevens-Johnson syndrome as an early allergic reaction to diphenylhydantoin].
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