Reznik L V
Vopr Med Khim. 1983 May-Jun;29(3):77-9.
Activity of cholinesterase was higher in young erythrocytes when the cell populations of various age were studied; the enzymatic activity was increased after addition of valinomycine into a medium independently on the antibiotic concentration and the enzyme activation was more pronounced in the old population of erythrocytes. The same alterations were observed in presence of calcium ionophore A 23187 and nystatin. Alterations in the enzymatic activity appear to depend on changes of erythrocyte membrane properties in ageing as well as on introduction of ionophore into the membrane.
在研究不同年龄的细胞群体时，年轻红细胞中的胆碱酯酶活性较高；无论抗生素浓度如何，向培养基中添加缬氨霉素后酶活性都会增加，且在老龄红细胞群体中酶的激活更为明显。在钙离子载体A 23187和制霉菌素存在的情况下也观察到了相同的变化。酶活性的改变似乎取决于衰老过程中红细胞膜特性的变化以及离子载体引入膜内的情况。
