葡甲胺泛影酸盐、甲泛葡胺和碘海醇用于颈动脉血管造影的双盲对比研究。
Comparative double-blind investigation of meglumine metrizoate, metrizamide, and iohexol in carotid angiography.
作者信息
Hindmarsh T, Bergstrand G, Ericson K, Olivecrona H
出版信息
AJNR Am J Neuroradiol. 1983 May-Jun;4(3):347-9.
The new nonionic contrast medium iohexol (Omnipaque) was compared with its predecessor metrizamide (Amipaque) and with the conventional ionic medium meglumine metrizoate (Isopaque Cerebral) in carotid angiography using a double-blind crossover technique. The results indicated that iohexol and metrizamide caused less discomfort than the ionic medium. The circulatory effects of the three media were generally mild, and the diagnostic effectiveness was comparable when the iodine concentration was kept in the range of 280-300 mg I/ml.
采用双盲交叉技术，将新型非离子型造影剂碘海醇（欧乃派克）与其前身甲泛葡胺（阿米培克）以及传统离子型造影剂葡甲胺泛影酸盐（异泛影葡胺脑用型）在颈动脉血管造影中进行比较。结果表明，碘海醇和甲泛葡胺引起的不适比离子型造影剂少。三种造影剂对循环系统的影响一般较轻，当碘浓度保持在280 - 300mg I/ml范围内时，诊断效果相当。
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