Westenskow D R, Jordan W S, Hayes J K
Anesth Analg. 1983 Sep;62(9):836-40.
A technique was studied for the rapid induction of anesthesia in a closed rebreathing circuit using feedback control of end-tidal enflurane concentration. This technique was compared to anesthetic induction using a constant inspired concentration. In one group of seven dogs, end-tidal enflurane concentration was maintained at 2.0%. Electronic feedback control automatically decreased the inspired concentration from a maximum of 3.7% to 2.1% during a 4-hr period. In the second group of seven dogs, the inspired enflurane concentration was 2.0% throughout the study. There was no statistically significant difference between the two groups with regard to enflurane uptake, heart rate, blood pressure, or cardiac output. Enflurane uptake was higher in the first group only during the first 6 min after induction. The induction technique that used feedback control to automatically adjust the inspired enflurane concentration appeared to have no adverse cardiovascular effects beyond those present during an induction using a constant inspired concentration.
研究了一种在紧闭式再呼吸回路中使用呼气末安氟醚浓度反馈控制来快速诱导麻醉的技术。将该技术与使用恒定吸入浓度进行麻醉诱导相比较。在一组7只犬中，呼气末安氟醚浓度维持在2.0%。电子反馈控制在4小时期间自动将吸入浓度从最高3.7%降至2.1%。在第二组7只犬中，整个研究过程中吸入安氟醚浓度为2.0%。两组在安氟醚摄取、心率、血压或心输出量方面无统计学显著差异。仅在诱导后的最初6分钟内，第一组的安氟醚摄取较高。使用反馈控制自动调节吸入安氟醚浓度的诱导技术，除了在使用恒定吸入浓度诱导期间出现的那些影响外，似乎没有不良心血管影响。
