Kano T, Notsuka T, Hiramoto Y, Abe Y, Masuda H, Kumashiro R, Inokuchi K
Gan To Kagaku Ryoho. 1983 Feb;10(2 Pt):278-82.
The effectiveness of postoperative adjuvant chemotherapy on aged patients (more than 70 years old) with resectable gastric carcinoma was examined in our Department. Of the 178 patients, 75 patients received the drugs on various regimen and 103 patients had no chemotherapy a control group). No significant difference was noted in patient characteristics of age, sex and curability. In advanced gastric carcinoma such as stage III and IV, a significant increase in long-term survival after surgery was obtained with combination chemotherapy or immunochemotherapy compared with the control group (P less than 0.05). On the other hand, there was no significant difference in a survival rate of the patients with stage I and II.
我们科室对老年(70岁以上)可切除胃癌患者术后辅助化疗的有效性进行了研究。178例患者中,75例接受了不同方案的药物治疗,103例患者未接受化疗(作为对照组)。在年龄、性别和可治愈性等患者特征方面未发现显著差异。在III期和IV期等进展期胃癌中,与对照组相比,联合化疗或免疫化疗使术后长期生存率显著提高(P<0.05)。另一方面,I期和II期患者的生存率没有显著差异。