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老年胃癌患者的辅助化疗

[Adjuvant chemotherapy for aged patients with gastric carcinoma].

作者信息

Kano T, Notsuka T, Hiramoto Y, Abe Y, Masuda H, Kumashiro R, Inokuchi K

出版信息

Gan To Kagaku Ryoho. 1983 Feb;10(2 Pt):278-82.

PMID:6410995
Abstract

The effectiveness of postoperative adjuvant chemotherapy on aged patients (more than 70 years old) with resectable gastric carcinoma was examined in our Department. Of the 178 patients, 75 patients received the drugs on various regimen and 103 patients had no chemotherapy a control group). No significant difference was noted in patient characteristics of age, sex and curability. In advanced gastric carcinoma such as stage III and IV, a significant increase in long-term survival after surgery was obtained with combination chemotherapy or immunochemotherapy compared with the control group (P less than 0.05). On the other hand, there was no significant difference in a survival rate of the patients with stage I and II.

摘要

我们科室对老年(70岁以上)可切除胃癌患者术后辅助化疗的有效性进行了研究。178例患者中,75例接受了不同方案的药物治疗,103例患者未接受化疗(作为对照组)。在年龄、性别和可治愈性等患者特征方面未发现显著差异。在III期和IV期等进展期胃癌中,与对照组相比,联合化疗或免疫化疗使术后长期生存率显著提高(P<0.05)。另一方面,I期和II期患者的生存率没有显著差异。

相似文献

1
[Adjuvant chemotherapy for aged patients with gastric carcinoma].老年胃癌患者的辅助化疗
Gan To Kagaku Ryoho. 1983 Feb;10(2 Pt):278-82.
2
[Effect of levamisole in postoperative adjuvant immunochemotherapy of stomach cancer--randomized controlled study of MMC-tegafur combination therapy with or without levamisole. 1].左旋咪唑在胃癌术后辅助免疫化疗中的作用——丝裂霉素-替加氟联合疗法加或不加左旋咪唑的随机对照研究。1
Gan To Kagaku Ryoho. 1982 Dec;9(12):2133-47.
3
[Comparison of immunochemotherapy and chemotherapy of stage IV gastric carcinoma].[IV期胃癌免疫化疗与化疗的比较]
Gan No Rinsho. 1985 Nov;31(14):1805-9.
4
Late results of postoperative long term cancer chemotherapy for advanced carcinoma of the stomach.进展期胃癌术后长期癌症化疗的远期疗效
Jpn J Surg. 1981;11(4):291-6. doi: 10.1007/BF02468770.
5
[Randomized study on the long-term adjuvant chemotherapy with ftorafur and mitomycin C for stomach cancer: second report].
Gan To Kagaku Ryoho. 1983 Nov;10(11):2408-17.
6
[Single chemotherapy with 5-fluorouracil or ftorafur and combination chemotherapy with mitomycin C and 5-fluorouracil for inoperable elderly gastric cancers].
Nihon Gan Chiryo Gakkai Shi. 1983 Feb 20;18(1):1-4.
7
[Randomized study of long-term adjuvant chemotherapy with Futraful and mitomycin C in gastric cancer. A second study (fourth report)].氟尿嘧啶与丝裂霉素C用于胃癌长期辅助化疗的随机研究。第二项研究(第四次报告)
Gan To Kagaku Ryoho. 1985 Sep;12(9):1833-9.
8
[Clinical study of PSK as an adjuvant immunochemotherapeutic agent against gastric cancer].[PSK作为胃癌辅助免疫化疗药物的临床研究]
Gan To Kagaku Ryoho. 1986 Aug;13(8):2532-7.
9
[Effect of postoperative long-term cancer chemotherapy (PLCC) on non-curative gastric cancer of stage IV].
Gan To Kagaku Ryoho. 1982 Apr;9(4):710-5.
10
[Surgery and adjuvant therapy of gastric cancer].
Gan To Kagaku Ryoho. 1986 Apr;13(4 Pt 2):1555-63.