Nicholson T, Omer S A
Br J Nutr. 1983 Jul;50(1):141-9. doi: 10.1079/bjn19830081.
Emulsions of C18 unsaturated fatty acids (FA) were infused for 2 h into the intestine of conscious sheep while motility of the reticulum and rumen was recorded. Statistically-significant depression of motility was found when 3 or 5 g FA/h were infused. At 1 g/h there were minor disruptions of motility. The inhibitory potency was not related to the extent of unsaturation of the FA. Receptors mediating the inhibitory effect were postulated to be distal to the iliac flexure of the duodenum, but the possible role of bile and pancreatic juice is discussed in relation to this problem. The probability that the effect was hormonally mediated is discussed.
将C18不饱和脂肪酸（FA）乳剂注入清醒绵羊的肠道2小时，同时记录网胃和瘤胃的运动情况。当以3克或5克FA/小时的速度注入时，发现运动性出现了具有统计学意义的抑制。以1克/小时的速度注入时，运动出现了轻微紊乱。抑制效力与FA的不饱和程度无关。据推测，介导抑制作用的受体位于十二指肠髂曲远端，但针对这个问题讨论了胆汁和胰液可能发挥的作用。还讨论了该效应由激素介导的可能性。
