Vuillaume M, Decroix Y, Calvayrac R, Vallot R, Best-Belpomme M
C R Seances Acad Sci III. 1983;296(18):845-50.
In Xeroderma pigmentosum (XP) a genetic-recessive ultraviolette-hypersensitive disease we found an accumulation of photoproduced H2O2 in skin cells accompanied by a breakdown of the catalatic activity. Both disorders intensified as the disease progressed. Concomitantly with these processes, one electrochemical peak of urine decreases. By the time epitheliomas appeared, this peak was no longer detectable. Several applications to the skin of a cream containing catalase seemed to prevent the formation and the evolution of neoplastic tumors during the treatment.
在色素性干皮病（XP）这种常染色体隐性紫外线过敏疾病中，我们发现皮肤细胞中光生成的过氧化氢有所积累，同时过氧化氢酶活性遭到破坏。随着病情发展，这两种紊乱情况都加剧了。与这些过程相伴的是，尿液的一个电化学峰降低。到上皮瘤出现时，这个峰就再也检测不到了。在治疗期间，向皮肤多次涂抹含过氧化氢酶的乳膏似乎能预防肿瘤的形成和发展。
