Pyerin W G, Hecker E
J Cancer Res Clin Oncol. 1983;106(1):71-3. doi: 10.1007/BF00399901.
Arylhydrocarbons are inducers of monooxygenase activity in epithelial cells in culture (Hela) whereas diterpene esters are not. This is one more example of a specific biochemical difference - here in gene activation - exhibited by tumor initiators and tumor promoters of the classes of compounds assayed.
芳烃是培养的上皮细胞(Hela细胞)中单加氧酶活性的诱导剂,而二萜酯则不是。这是所检测的各类化合物中的肿瘤启动剂和肿瘤促进剂表现出的特定生化差异——此处是基因激活方面差异——的又一个例子。