Nichols B L, Garza C, Klish W, Hazlewood C, Argote R M, Garcia G, Parra A
J Pediatr Gastroenterol Nutr. 1983;2(1):50-6. doi: 10.1097/00005176-198302010-00006.
Muscle electrolyte composition has been studied in 10 infants with marasmus and eight children with kwashiorkor. The presence of altered muscle salt and water concentrations was confined in the latter nutritional syndrome. The marasmic infant, with equivalent or more severe nutritional wasting than the child with kwashiorkor, maintained a more normal muscle electrolyte concentration as indicated by a number of criteria. The pathophysiology of the altered muscle composition in kwashiorkor remains unclear; however, it appears to be more specific than due just to a depletion of available fat and muscle stores. Although possible endocrine mechanisms can be postulated to explain the change in muscle chemistry, the existing evidence is inadequate. Clearly, continuing research is warranted.
对10名患消瘦症的婴儿和8名患夸希奥科病的儿童的肌肉电解质成分进行了研究。肌肉盐和水浓度的改变仅存在于后一种营养综合征中。与患夸希奥科病的儿童相比，患消瘦症的婴儿营养消耗程度相当或更严重，但从多个标准来看，其肌肉电解质浓度保持得更为正常。夸希奥科病中肌肉成分改变的病理生理学尚不清楚；然而，这似乎比仅仅由于可用脂肪和肌肉储备的消耗更为特殊。尽管可以假定可能的内分泌机制来解释肌肉化学变化，但现有证据并不充分。显然，有必要继续进行研究。
