Gleicher N, Siegel I
Wien Klin Wochenschr. 1983 May 27;95(11):377-82.
Even though the paradox of the fetal allograft is still not completely understood, advances in reproductive immunology have made various immunological mechanisms apparent which seem to play a part in the tolerance of the fetal allograft by a seemingly normal maternal immune system. Pregnancy immunology is, however, not only restricted to the understanding of the transplant analogy of pregnancy, but has also achieved clinical significance through our increased awareness of immunological mechanisms being implicated in various pregnancy disorders. A review is presented outlining our present understanding of both basic immunological mechanisms and the normal process of pregnancy as well as those abnormal mechanisms which may be implicated in pathological states.
尽管胎儿同种异体移植的悖论仍未被完全理解，但生殖免疫学的进展已使各种免疫机制变得明显，这些机制似乎在看似正常的母体免疫系统对胎儿同种异体移植的耐受性中发挥作用。然而，妊娠免疫学不仅局限于理解妊娠的移植类比，还通过我们对涉及各种妊娠疾病的免疫机制的更多认识而具有了临床意义。本文综述了我们目前对基本免疫机制、正常妊娠过程以及可能与病理状态相关的异常机制的理解。
