Tur'ianov M Kh, Lomazova K D, Kazanskaia L V, Chumakova Z V, Poliakova A M
Biull Eksp Biol Med. 1983 Sep;96(9):33-5.
The platelet aggregation reaction was used to assess the influence of arachidonic acid (AA), endotoxin (E) S. typhimurium and ADP on platelet aggregation properties. All the three substances induced platelet aggregation. A higher degree of aggregation was attained by the application of E combined with AA and ADP as compared with the effects produced by E and ADP alone. Prolonged incubation of platelet-rich plasma (PRP) samples with E led to an essential decrease of the aggregation degree on ADP addition. Incubation of PRP samples with E and ADP did not evoke any analogous decrease in the platelet aggregation degree. The data obtained indicate that AA stimulates platelet aggregation induced by E and ADP.
采用血小板聚集反应来评估花生四烯酸（AA）、内毒素（E）、鼠伤寒沙门氏菌和二磷酸腺苷（ADP）对血小板聚集特性的影响。这三种物质均能诱导血小板聚集。与单独使用E和ADP相比，联合应用E、AA和ADP可使血小板聚集程度更高。富含血小板血浆（PRP）样本与E长时间孵育会导致加入ADP后聚集程度显著降低。PRP样本与E和ADP一起孵育并未引起血小板聚集程度的类似降低。所获得的数据表明，AA可刺激由E和ADP诱导的血小板聚集。
