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红细胞压积升高的真性红细胞增多症中的腔隙性梗死

Lacunar infarcts in polycythaemia with raised packed cell volumes.

作者信息

Pearce J M, Chandrasekera C P, Ladusans E J

出版信息

Br Med J (Clin Res Ed). 1983 Oct 1;287(6397):935-6. doi: 10.1136/bmj.287.6397.935.

DOI:10.1136/bmj.287.6397.935
PMID:6412894
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1549171/
Abstract

Lacunar (small deep cerebral infarcts) infarction is described in association with raised packed cell volumes. Two patients had polycythaemia vera, one stress polycythaemia. They presented with transient ischaemic episodes and were shown by computed tomography to have lacunes deep in the basal ganglia and internal capsule. Such lesions may be caused by small vessel occlusions related to increased viscosity and impaired oxygen consumption by adjacent tissues. Finding a raised packed cell volume in patients with lacunes and transient ischaemic attacks offers a further possibility of treatment.

摘要

腔隙性(小的深部脑梗死)梗死与血细胞比容升高有关。两名患者患有真性红细胞增多症,一名患有应激性红细胞增多症。他们表现为短暂性缺血发作,计算机断层扫描显示基底节和内囊深部有腔隙。此类病变可能由与血液粘度增加及邻近组织氧消耗受损相关的小血管闭塞引起。在患有腔隙性梗死和短暂性缺血发作的患者中发现血细胞比容升高为治疗提供了进一步的可能性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4992/1549171/71dba2a96183/bmjcred00573-0014-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4992/1549171/0f2f25014bce/bmjcred00573-0014-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4992/1549171/71dba2a96183/bmjcred00573-0014-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4992/1549171/0f2f25014bce/bmjcred00573-0014-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4992/1549171/71dba2a96183/bmjcred00573-0014-b.jpg

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本文引用的文献

1
LACUNES: SMALL, DEEP CEREBRAL INFARCTS.腔隙性脑梗死:小而深的脑梗死灶。
Neurology. 1965 Aug;15:774-84. doi: 10.1212/wnl.15.8.774.
2
Neurologic complications of polycythemia.红细胞增多症的神经系统并发症
Ann Intern Med. 1962 Dec;57:909-16. doi: 10.7326/0003-4819-57-6-909.
3
Lacunar strokes and infarcts: a review.腔隙性卒中与梗死:综述
脑梗死的非动脉粥样硬化病因。
Postgrad Med J. 1984 Jun;60(704):386-90. doi: 10.1136/pgmj.60.704.386.
4
The haemorheological features of lacunar strokes.
J Neurol. 1985;232(6):357-62. doi: 10.1007/BF00313836.
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Pseudopolycythaemia and coeliac disease.假性红细胞增多症与乳糜泻。
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Neurology. 1982 Aug;32(8):871-6. doi: 10.1212/wnl.32.8.871.