Grichois M L, Franck D, De Mendonca M
C R Seances Acad Sci III. 1983;296(15):735-7.
A system exchanging extracellular Na+ against intracellular Na+ in a one to one ratio has been characterized in human erythrocyte. The function of this system is not yet shown, however its activity is altered in some hypertensive or manic depressives. Its activity can be determined by measuring the rate of Na+ flux in the presence in the extracellular medium, of lithium, ouabain and bumetanide. It is inhibited by phloretin. In this work, a similar flux has been demonstrated in Rat erythrocyte.
在人类红细胞中已鉴定出一种以一对一比例将细胞外钠离子与细胞内钠离子进行交换的系统。然而，该系统的功能尚未明确，但在一些高血压患者或躁郁症患者中其活性会发生改变。其活性可通过在细胞外培养基中存在锂、哇巴因和布美他尼的情况下测量钠离子通量速率来确定。它会被根皮素抑制。在这项研究中，在大鼠红细胞中也证实了类似的通量。
