Girton J R
Dev Biol. 1983 Sep;99(1):202-9. doi: 10.1016/0012-1606(83)90268-3.
The growth of pattern triplications induced by a 48-hr 29 degrees C treatment given to larvae homo- or hemizygous for a ts cell-lethal mutation was examined to determine which structures result from new, regulative growth and which are produced by the original imaginal disc cells. Pattern triplications contain one complete leg pattern (orthodrome) and two partial patterns (antidrome and paradrome). The results of two morphological analyses and one somatic clonal analysis suggest that in triplications in which the antidrome and paradrome become more complete distally (diverge) the paradrome is formed by a portion of the original leg pattern, and the antidrome and orthodrome are formed by extra, regulative growth. A different result is suggested for triplications in which the antidrome and paradrome become less complete distally (converge). In these, the orthodrome appears to be formed by the original leg pattern and the antidrome and paradrome by extra growth. These results agree with predictions based on the polar coordinate model of positional information.
对携带温度敏感型细胞致死突变的纯合或半合子幼虫进行48小时29摄氏度处理所诱导的模式重复生长进行了研究，以确定哪些结构是由新的调节性生长产生的，哪些是由原始成虫盘细胞产生的。模式重复包含一个完整的腿部模式（正向）和两个部分模式（反向和旁向）。两项形态学分析和一项体细胞克隆分析的结果表明，在反向和旁向在远端变得更完整（发散）的重复中，旁向由原始腿部模式的一部分形成，而反向和正向由额外的调节性生长形成。对于反向和旁向在远端变得不那么完整（汇聚）的重复，结果则不同。在这些重复中，正向似乎由原始腿部模式形成，而反向和旁向由额外生长形成。这些结果与基于位置信息的极坐标模型的预测一致。
