Morata G, Kornberg T, Lawrence P A
Dev Biol. 1983 Sep;99(1):27-33. doi: 10.1016/0012-1606(83)90250-6.
The eye-antenna imaginal disc of Drosophila is subdivided into anterior and posterior compartments and it is expected therefore that the engrailed gene would be locally required in the posterior compartment. Here we describe the phenotype of engrailed mutations in the antenna. Clones of cells which were mutant for en1/enC2 were produced in wild-type antennae by mitotic recombination. The clones showed the typical syndrome of cells mutant for engrailed, being normal in the anterior compartment and showing partial posterior-to-anterior transformation in the posterior compartment.
果蝇的眼触角成虫盘被分为前区和后区，因此预期engrailed基因在后区是局部必需的。在此我们描述engrailed突变在触角中的表型。通过有丝分裂重组在野生型触角中产生了en1/enC2突变的细胞克隆。这些克隆表现出engrailed突变细胞的典型综合征，在前区正常，在后区表现出部分后向前的转化。
